Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid)
Deacetyl asperulosidic acid
CAS: 14259-55-3
Molecular Formula: C16H22O11
Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid) - Names and Identifiers
Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid) - Physico-chemical Properties
| Molecular Formula | C16H22O11 |
| Molar Mass | 390.34 |
| Density | 1.73 |
| Boling Point | 744.1±60.0 °C(Predicted) |
| Specific Rotation(α) | (c, 1.7 in MeOH)+26 |
| Solubility | Soluble in water, alkaline solution, insoluble in petroleum ether. |
| Appearance | White powder |
| pKa | 4.34±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD21364062 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, ethyl acetate, almost insoluble in water, from the pig, Morinda officinalis, Hedyotis diffusa. |
Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid) - Reference
| Reference Show more | 1. Shen Yu, he Yuqiong, Zhang Qi, Liu mengqin, Xinhai, Zhang Quan-long, Qin Lu-ping, Zhang Qiaoyan. Preparation of iridoid glycosides from Morinda officinalis how and their inhibitory effect on bone resorption of osteoclasts [J]. Academic Journal of Second Military Medical University, 2019,40(02):149-156. 2. Shi Yuehua, Yan Qiuying, fan Huisen et al. Simultaneous determination of three diterpenoids in rat plasma by UHPLC-MS/MS after intragastric administration of hedyotis diffusa aqueous extract and its pharmacokinetics [J]. Journal of Pharmaceutical Analysis, 2019, 039(005):813-820. 3. He, Jingyu, et al. "Asperuloside and asperulosidic acid entert an anti-ignition effect via inhibition of the NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages." International journal of molecular sciences 19.7 (2018): 2027.https:// 4. [IF = 4.183] Jingyu He et al."Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages."Int J Mol Sci. 2018 Jul;19(7):2027 5. [IF=3.659] Shen Yi et al."Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats."Bmc Complem Altern M. 2018 Dec;18(1):1-12 6. [IF=5.878] Li DanQing et al."N-butanol extract of Hedyotis diffusa protects transgenic Caenorhabditis elegans from Aβ-induced toxicity."Phytother Res. 2021 Feb;35(2):1048-1061 7. [IF=5.34] Wei Zou et al."Imperatae rhizoma-Hedyotis diffusa Willd. herbal pair alleviates nephrotic syndrome by integrating anti-inflammatory and hypolipidaemic effects."Phytomedicine. 2021 Sep;90:153644 8. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9 |
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